Bias in Pharmaceutical Development, Promotion, and Regulation

John has developed a conceptual and empirical methodology for defining and identifying bias in industrial drug testing and government pharmaceutical regulation. This involves first identifying technical inconsistencies in discourse and practices between the technical standards (or stances) agreed/taken publicly by medical scientists/doctors, on the one hand, and claims that they subsequently make often within specific drug testing or regulatory decision-making, on the other. Secondly, he then maps the technical inconsistencies on to the commercial and/or institutional interests of stakeholders, such as the pharmaceutical industry, government regulatory agencies, the medical profession and/or patient organizations. This theme is exemplified in the following publications:

John Abraham Science, Politics and the Pharmaceutical Industry, 310pp, UCL Press, 1995.

John Abraham (1994) ‘Bias in Science and Medical Knowledge: The Opren Controversy‘ Sociology: the official journal of the British Sociological Association 28: 717 36.

John Abraham (2008) ‘Sociology of pharmaceutical development and regulation: a realist empirical research programme’ Sociology of Health & Illness 30 (6): 869-8.

John Abraham (2026) ‘The Political Economy of Bias: the Case of the Pharmaceutical Sector’ at International Public Policy conference on Corporate Power and Public Policy, Carleton University, Ottawa, July.

John Abraham and Gowree Balendran (2026) ‘Inside the “Black Box” of Pharmaceuticalisation: NICE, the Permissive Principle and the case of Anti-coagulants’ Sociology of Health & Illness 48 (8), 16 October 2026, pp.1-14, doi.org/10.1111/1467-9566.70279

John Abraham (1993) ‘Scientific Standards and Institutional Interests: Carcinogenic Risk Assessment of Benoxaprofen in the UK and the US‘ Social Studies of Science 23: 387-444.

John Abraham and Courtney Davis (2009) ‘Drug evaluation and the permissive principle: continuities and contradictions between standards and practices in antidepressant regulation’ Social Studies of Science 39: 569-98.

John Abraham (2002) ‘Drug safety and the safety of patients: the challenge to medicine and health from permissive expert assessments’ Health, Risk & Society 4: 19-29.

John Abraham (2008) ‘Bias and science in knowledge production: implications for the politics of drug regulation’ in (eds.) O. O’Donovan & K. Glavanis-Grantham, Power, Politics and Pharmaceuticals, pp. 43-57, Cork University Press.

John Abraham and Julie Sheppard (1999) ‘Complacent and conflicting scientific expertise in British and American drug regulation: clinical risk assessment of triazolam’ Social Studies of Science 29: 803-43.

John Abraham (1994) ‘Negotiation and Accommodation in the Production of Expert Medical Risk Assessment‘ Policy Sciences 27: 53-76.

John Abraham (2010) ‘The pharmaceutical industry and medications’ in (eds.) P. Conrad, C. Bird, A. Freemont & S. Timmermans, American Sociological Association Handbook of Medical Sociology, pp. 290-308 (Nashville: Vanderbilt University Press).

John Abraham (2010) ‘Les principaux defis sociopolitique de la mise au point des produits pharmaceutiques, de leur reglementation et de la santé publique (Key socio-political challenges of pharmaceutical development, regulation and public health)’ in (eds.) C. Garnier & Anne-Laure Saives, Turbulences dans la Chaine des Medicaments, pp. 121-54 (Montreal: Liber).